Keywords such as “T2DM,” "Type 2 Diabetes Mellitus," “SGLT2i,” "Sodium-glucose cotransporter-2 inhibitors," “DPP-4 inhibitors,” “Biguanides,” “Metformin,” and “GLP-1 RA” were utilized to identify recent and relevant findings. This evidence concerns the gene GLP1R and type 2 diabetes mellitus.