VGLL3 and autoimmune disease: It is worth noting that whereas VGLL3 seems to be enriched in the skin of women and is associated with female-biased autoimmune diseases, YAP1 is associated with pro-oncogenic signaling (Johnson and Halder, 2014; Morciano et al, 2021), and the incidence of cancer is higher in men (Kim et al, 2018).