VGLL3 and autoimmune disease: This broader role in sex-biased autoimmune diseases suggests that VGLL3 could be an attractive therapeutic target; however, VGLL3 intersects with the Hippo pathway, a conserved signaling network that plays a central role in various cellular process required for cell proliferation and differentiation, organ growth, embryogenesis, and tissue regeneration/wound healing (Fu et al, 2022).