C1QTNF5 and type 2 diabetes mellitus: ⁃ Subjects with T2D and IGT had higher circulating myonectin concentrations than normal subjects.⁃ A 45-minute exercise period did not change circulating myonectin levels.⁃ Plasma myonectin does not change significantly with an oral glucose tolerance test, EHC, or lipid infusion (in young individuals).