- Higher Myonectin and CTRP7 levels in individuals with IGT and T2D compared to NGT.- Serum Myonectin+CTRP7 positively correlates with IR indicators like HOMA-IR, HbA1c, TG, and FFA; negatively correlates with adiponectin.- Myonectin+CTRP7 is a better risk predictor for T2D and IR than Myonectin or CTRP7 alone.⁃ CTRP7 increases with high insulin and exercise; myonectin shows minimal changes. Here, INS is linked to type 2 diabetes mellitus.