The airway presents a more complex GSH profile; while BALF from CF patients and CFTR-deficient models typically shows depleted GSH, exacerbated by infection (Gould et al., 2010; Kettle et al., 2014; Dickerhof et al., 2017), sputum studies have surprisingly reported higher total GSH (Dauletbaev et al., 2004). The gene discussed is CFTR; the disease is cystic fibrosis.