HLA-DRB1 and interstitial lung disease: Other biomarkers have been identified as related to ILD such as anti-carbamylated proteins (Anti-CarP), Krebs von den Lungen 6/MUC1 (KL-6), as well as a genetic background including predisposing genes such as HLADRB1*15, HLADRB1*16, DQB1*06, and HLA-A*31:01, or single nucleotide variations of MUC5B gene (11, 24).