Abnormal expressions of RGC32 have been found in some solid tumors, such as high expression in colorectal (6, 29), pancreatic (5, 30), breast (31), Renal Cell Carcinoma (32), ovarian (33), but low expression in astrocytoma (19, 34) and adrenocortical carcinoma (35). The gene discussed is RGCC; the disease is astrocytoma (excluding glioblastoma).