ZDHHC9 and breast cancer: In addition, IHC experiments revealed that in human BC tissues with high expression of ZDHHC9, the proportion of macrophage (CD68) infiltration was higher than that in the tissues with low expression of ZDHHC9, and in BC tissues with low expression of ZDHHC9, macrophages were more inclined to polarize towards M2 (CD206) (Figures 8F, G).