This study investigates immunoglobulins (Ig)G, IgM, and IgA responses to EBV nuclear antigen EBNA (peptide 386–405), HHV-6 (peptide 300–322) and EBV (peptide 243–268) deoxyuridine-triphosphatase (dUTPase), and different immune profiles in 58 patients with relapsing remitting MS (RRMS) compared to 60 healthy controls. Here, CD79A is linked to relapsing-remitting multiple sclerosis.