NIT1 expression in NSCLC cells was significantly associated with poor differentiation of cancer cells, advanced TNM stages (III versus I+II), lymph node metastasis and poor clinical outcome of the patients ((60.70 ±5.48 vs 30.83 ± 4.88 months) (Table 1 and Figure 1) (p < 0.05). The gene discussed is NIT1; the disease is metastatic malignant neoplasm in the lymph nodes.