The difference in AUC between CA125+HE4+NLR+PLR+MLR+SII and CA125+HE4+PLR+MLR+SII for diagnosing EOC was not statistically significant (P = 0.9305), but there was a statistically significant difference in AUC when compared with other tumor and inflammatory markers for diagnosing EOC (P < 0.05) (Figure 5). This evidence concerns the gene MUC16 and neoplasm.