WFDC2 and ovarian benign neoplasm: When assessing the levels of CA125, HE4, NLR, PLR, MLR, and SII in both the preoperative blood of EOC and benign ovarian tumor cohorts, it was observed that the EOC group exhibited significantly elevated measurements of CA125, HE4, NLR, PLR, MLR, and SII compared to the benign ovarian tumor group.