LDL/HDL ratio, triglyceride‐glucose index (TyG), atherogenic index of plasma (AIP), single‐point insulin sensitivity estimator (SPISE) index, oxidized LDL (Ox‐LDL), intercellular adhesion molecules (ICAM‐1 and E‐selectin), as well as the marker of oxidative DNA damage were compared among 150 offspring of diabetic parents (90 normoglycemic and normotolerant offspring, 31 offspring with impaired fasting glucose (IFG), and 29 offspring with impaired glucose tolerance (IGT)), and 40 age‐and sex‐matched healthy control individuals. The gene discussed is INS; the disease is Impaired glucose tolerance.