HMGB1 and Hyperglycemia: Abbreviations: ACS, acute coronary syndrome; CH3, citrullinated histone H3; CI, confidence interval; GDMT, guideline‐directed medical therapy; GRACE, Global Registry of Acute Coronary Events; HMGB1, high mobility group box‐1 protein; HR, hazard ratio; LPA, lysophosphatidic acid; MACE, major adverse cardiovascular events; PAGln, phenylacetylglutamine; PDGF, platelet‐derived growth factor; SHR, stress hyperglycemia ratio; TyG, triglyceride‐glucose.