BAX is an important regulatory protein for mitochondrial stability, and it translocates from cytoplasm to mitochondrial membrane, then promoting a release of cytochrome c and cardiomyocyte apoptosis.[42, 45] As a consequence, BAX‐mediated mitochondrial damage and myocardial apoptosis further cause MH and other heart diseases.[49, 64, 65] Zeng et al. The gene discussed is CYCS; the disease is heart disorder.