This regulatory function of ALKBH5 is mediated through its influence on m6A modifications, highlighting its ability as a therapeutic target in controlling NSCLC progression and metastasis.318 TGF-β is a potent inducer of EMT, and through this process, it not only promotes metastasis but also contributes to immune evasion by reducing the expression of epithelial antigens that could be recognized by the immune system. This evidence concerns the gene TGFB1 and non-small cell lung carcinoma.