TAMs aid immune evasion by suppressing CD8+ T cell and NK cell functions, promoting tissue remodeling and angiogenesis, and supporting tumor growth and metastasis.109 M2-TAMs play crucial roles in cancer progression by fostering immune evasion,109,110 tissue remodeling,111 and tumor growth.110,112 They inhibit CD8+ T cell and NK cell functions, enabling tumors to evade immune surveillance. Here, CD8A is linked to cancer.