DSP pLoF variants were enriched in UKB females with DCM (DSP PAV 5.2% in females, 2.9% in males, OR 1.8, CI 0.94-3.4; DSP pLOF 2.3% in females, 0.22% in males, OR 10.9: 95% CI: 2.2-104.0). This evidence concerns the gene DSP and familial dilated cardiomyopathy.