GPT and chronic hepatitis B virus infection: Serum concentrations of bilirubin, AST, and ALT are predictive of mortality in patients with acute and chronic HF.68, 69, 70 For other chronic liver diseases including chronic hepatitis B, hepatitis C, and MASLD, the AST to platelet ratio index and fibrosis-4 scores have been developed to predict the risk of hepatic fibrosis.