Fig 5 presents that the DCM group revealed a marked elevation in cardiac content of NLRP3 inflammasome as well as a prominent augmentation of cardiac content of IL-1β, by 3.2- and 2.9-fold related to the normal control group, indicating the initiation and exacerbation of diabetic cardiomyopathy due to inflammatory cascades. Here, NLRP3 is linked to familial dilated cardiomyopathy.