In Fig 7, the DCM rats evoked an increase of 6-fold of the cardiac inflammatory marker NF-κB gene expression, which induces the inflammatory events mediated by the pro-inflammatory TLR-4 thus resulting in a significant upsurge in cardiac TLR-4 gene expression, by 4.5-fold of the normal control group. Here, TLR4 is linked to familial dilated cardiomyopathy.