To shed light on the putative mechanism by which endogenous cathelicidin regulates mucin secretion in colonic goblet cells in response to infection, we focused on ROS that regulates mucin secretion in the colon.20 By bulk RNA-seq transcript analysis, there was an upregulation of genes associated with detoxification of ROS during peak C. rodentium infection in Camp-/- compared to Camp+/+ littermates (Figure 8A; Table S1). Here, MUC5AC is linked to infection.