Excess iron accumulation has been found to inhibit maternal hepcidin production or activity, leading to continued absorption of dietary iron, increasing blood viscosity, clogging blood vessels, and reducing placental perfusion.23 Zhu et al.24 used a preeclampsia rat model to evaluate the effects of ferritin concentration and ferroptosis levels at different stages of pregnancy on placental function. The gene discussed is HAMP; the disease is preeclampsia.