In predicting the factors influencing the changes in elevated anti-TG and anti-TPO levels, Type-I DM and women were found to besignificant (elevated anti-TG, Exp (B): 3.863, 2.543, p: 0.028; 0.035; elevated anti-TPO, Exp (B): 4.862, 3.142, p: 0.005, 0.005). This evidence concerns the gene TPO and diabetes mellitus.