The process is mediated by glucose transporters (especially GLUT1) (Heydarzadeh et al., 2020), and the increased expression of GLUT1 has been linked to lower survival rates for various types of cancers, including gastric cancer, thyroid cancer, and breast cancer (Weng et al., 2022; Xu et al., 2020). The gene discussed is SLC2A1; the disease is breast cancer.