Xing et al. further revealed that miR-612 promotes HCC ferroptosis through HADHA-mediated regulation of the mevalonate pathway, downregulating CoQ10 while elevating intracellular PUFA levels and lipid peroxidation, thereby inhibiting HCC proliferation and metastasis (Xing et al., 2023). This evidence concerns the gene HADHA and hepatocellular carcinoma.