Ten days after the induction of GN (Figure 1M), we found significantly improved kidney injury outcomes in mice given anti-IFN-γ mAb, with decreased proteinuria (Figure 1N) and attenuated severity of glomerular damage (glomerular segmental necrosis, glomerular macrophages, and glomerular CD4+ T cells, Figures 1O–Q). Here, CD4 is linked to ganglioneuroma.