IL2 and allergic disease: For instance, it has been shown that children with both asthma and type 1 diabetes have a unique pattern of cytokines conducive with a combined TH1/TH2 profile,45,46 that children with allergic disease have increased IL-2 levels (an important TH1 signaler),47 and that other regulatory subtypes of T cells, including TH17, partake in inflammation in both asthma and type 1 diabetes.3