In terms of biochemical index statistics, FPG and HbA1c showed a decreasing trend in the T2DM, OB and HC groups; in addition, compared with the HC group, ALT, AST, TC, TG and LDL-C were significantly higher in the T2DM group, and ALB, HDL-C and UREA were significantly lower in the T2DM group; compared with the HC group, HbA1c, ALT and AST in the OB group were higher than that of the HC group, and the above were statistically different (p < 0.05). The gene discussed is ALB; the disease is type 2 diabetes mellitus.