TIMP1 and fibrosis: The ELF test, which measures hyaluronic acid, TIMP-1, and PIIINP, is validated as a fibrosis staging tool and has shown prognostic value in predicting liver-related events [84]. Likewise, the FibroScan-AST (FAST) score, combining transient elastography (TE) and AST, enables identification of patients with active MASH and significant fibrosis in a non-invasive manner [85].