CXCR3 and neoplasm: [291] METTL3 or METTL14 deletion in tumor cells increases STAT1 and IRF1 mRNA abundance in an m6A-decay mechanism, and thus further elevates the CXCL9 and CXCL10, two essential chemokines can recruit the effector T cells or NK cells expressing CXCR3 into tumor, indicating that m6A-mediated chemokines contribute immune cell infiltration.