ALK and cancer: To systemically identify potential targets for ALK+ ALCL, we analyzed the Cancer Dependency Map (DepMap, https://depmap.org/portal/), which contains the essential genes for cancer cell survival and molecular characterization of over 1000 cell lines by conducting genome‐wide CRISPR and shRNA screens and integrating data from multiple sources including Cancer Cell Line Encyclopedia (CCLE).[16] By leveraging DepMap's extensive datasets and analytical tools, five ALCL cell lines (SUDHL1, Karpas299, KIJK, SUPM2, and DEL) were characterized, all of which demonstrated ALK positivity.