The results show that the expression of Cav1.2 is significantly decreased in the infarct border zone at 12 h post-MI.CDR1as knockdown via AAV9-CDR1as-shRNA administration leads to an enhancement of cardiac function and a restoration of bothICaL density and Cav1.2 expression in MI model mice. Here, LINC00632 is linked to myocardial infarction.