A more recent trial (NCT02943850) tested neural progenitors engineered to secrete glial cell line‐derived neurotrophic factor (CNS10‐NPC‐GDNF) in ALS, demonstrating successful engraftment, GDNF expression, and no negative impact on motor function (Baloh et al. 2022). Here, GDNF is linked to amyotrophic lateral sclerosis.