Convalescent plasma collected from recovered COVID-19 patients in 2020 (2020-CP) and 2022 (2022-CP), as well as post-infection hyperimmunoglobulin lots (pi-hCoV-2IG), showed high neutralization titers against the WA-1 but demonstrated minimal or no PsVNA titers against the recent Omicron variants (Figure 1 and Supplementary Table S2). The gene discussed is CP; the disease is COVID-19.