Additionally, the proportions of MHC Ihigh DCs and MHC IIhigh DCs were significantly elevated in the P1 (15 mg/kg) and P1 (10 mg/kg) groups, indicating that the Vpr peptide promoted the maturation of DCs in the lymph nodes and enhanced their ability to present tumor antigens (Figure 6A,B). This evidence concerns the gene HLA-C and neoplasm.