Interestingly, increased epidermal expression of TLRs has been observed in MF lesions (TLR-2, TLR-4, and TLR-9) [16] and in CD30+ cutaneous lymphomas (TLR-2, TLR-4, TLR-7, and TLR-9) [17]. Here, TNFRSF8 is linked to mycosis fungoides.