IL2RB and Epstein-Barr virus infection: Additionally, EBV miRNAs ebv-miR-BART14-3p and ebv-miR-BART5-3p both target the interleukin 2 receptor subunit beta (IL2RB) transcript [117], which is important for regulating various interleukin pathways, leading to more severe EBV infection, as reduction in IL2RB interferes with T-cell mediated antiviral immunity [118].