JAK2 and cervical cancer: A study conducted with HPV-positive cervical cancer samples revealed that inhibition of JAK2 mediated by miR-204-5p present in E6+ exosomes, extracellular vesicles secreted by HPV-infected cells containing the E6 oncogene, promoted macrophage polarization toward the M2 phenotype, contributing to the progression of HPV-associated cervical lesions [42].