IFNA1 and neoplasm: The above is relevant, since it has been proven that the production of IFNα helps the activation of cytotoxic cells such as natural killer cells, in addition to the increase in the expression of class I MHC molecules, which promotes the recognition of tumor cells by CD8 T lymphocytes [28,29], which are all essential elements in the antitumor immune response needed to reduce tumor size and improve survival [30].