An investigation on the effects of miR-7a in a spinal SNL rat model using an AAV inhibited the activation of the signal transducer and activator of the transcription 3 (STAT3) signaling pathway and relieved neuropathic pain, proving it to be a significant and potential treatment for neuropathic pain patients (Figure 4) [98]. Here, STAT3 is linked to neuropathic pain.