EGFR and hepatocellular carcinoma: Interestingly, the antitumor efficacy of rLZ-8 on five patient-derived tumor xenograft (PDX) models of HCC (LI6280, LI1097, LI0050, LI0334, LI6611) was directly correlated with tumoral EGFR expression levels, suggesting the mechanistic involvement of EGFR.