MPO and colitis: The colitis control group of animals recorded a significant increase in MPO concentration compared with the non-colitis control, and treatment with 3 mg/kg (low dose) did not significantly reduce the MPO concentration, and 30 mg/kg and 100 mg/kg treated animals recorded a significant (p > 0.001) reduction compared with the colitis control animals in a dose-dependent manner (Figure 2B, Table 3).