The activation of Signal Transducer and Activator of Transcription proteins (STAT), especially Signal Transducer and Activator of Transcription 3 (STAT3), a transcription factor regulating genes related to cell growth, survival, and immunity, is heavily involved in cancer development across many tissues and inflammatory responses in cancers of the stomach, liver, lung, colon, and pancreas. Here, SOAT1 is linked to cancer.