The inhibition of this interaction by Anthocyanidin helps explain its anti-inflammatory activity, especially since IL-17A is a key cytokine involved in numerous chronic inflammatory conditions, such as rheumatoid arthritis, multiple sclerosis, experimental autoimmune encephalomyelitis (EAE), allergen-induced pulmonary inflammation, psoriasis, and cancer [156,157,158,159,160]. This evidence concerns the gene IL17A and rheumatoid arthritis.