EGFR and non-small cell lung carcinoma: Furthermore, EGFR gene copy number amplification was more likely to occur in EGFR mutant NSCLC, as shown in Figure 4B. The increase in gene copy number was positively correlated with the expression of EGFR, and the expression of EGFR, including transcript level and translation level, was significantly higher in EGFR gene copy number amplification samples relative to normal diploids (Figure 4C).