Of all 2485 publications, 234 were cited more than 200 times, with the most frequently cited publication being “Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity” (1868 citations), followed by “Metabolic syndrome and altered gut microbiota in mice lacking toll-Like receptor 5” and “Gastroenterology 2-inflammatory bowel disease: clinical aspects and established and evolving therapy”. The gene discussed is TLR5; the disease is obesity due to melanocortin 4 receptor deficiency.