Between the first and second presentations, and according to the proposed classification [18,28], there were two confirmed primary CMV infections that showed an IgM positive/IgG negative profile with seroconversion to IgM negative/IgG positive (one case) and an IgM/IgG negative profile with seroconversion to IgM positive/IgG negative (one case). Here, CD40LG is linked to cytomegalovirus infection.