YAP1 and metastatic malignant neoplasm in the lymph nodes: Several previous studies have concluded with conflicting results regarding the prognostic and predictive role of YAP1 in breast cancer; Cha et al. demonstrated that high nuclear YAP1 expression was associated with HR negativity, increased Ki-67 index, lymph node metastasis, and inferior distant metastasis-free and disease-free survival (DFS), particularly in TNBC patients (HR for DFS: 3.208, p = 0.0105; HR for DMFS: 2.384, p = 0.0367) [21].