Various studies have explored the correlation between vitamin D-specific receptors and susceptibility to psoriasis [122,123]; it has been discovered that the A-1012G promoter polymorphism of the vitamin D receptor (VDR) gene is linked to an increased risk of psoriasis due to reduced expression of VDR mRNA, which may contribute to changes in the cutaneous barrier and the formation of psoriatic lesions [124]. The gene discussed is VDR; the disease is psoriasis.