In contrast, VPS26A expression was significantly downregulated in several tumor types, including glioblastoma multiforme (GBM), kidney chromophobe (KICH), kidney renal papillary cell carcinoma (KIRP), prostate adenocarcinoma (PRAD), rectal adenocarcinoma (READ), thyroid carcinoma (THCA), and uterine corpus endometrial carcinoma (UCEC). The gene discussed is VPS26A; the disease is glioblastoma.