In this context, Maresin 1 (MaR1), a lipid-derived pro-resolving mediator involved in the resolution of inflammation, and Chitinase-3-like protein 1 (CHI3L1), a glycoprotein associated with immune response, tissue remodeling, and fibrosis, have become focal points in research related to diabetes and its complications. This evidence concerns the gene CHI3L1 and diabetes mellitus.