Moreover, the frequencies of B-ALL patients carrying p.P348L and rs374987145 in the A20 gene and rs1230581026 and rs1647843460 in the Cezanne gene were higher in the low-A20/Cezanne-expression group, while the frequency of B-ALL patients carrying p.K337Q were lower in the low-A20-expression group only, as compared to those with high A20 expression (Table 5). This evidence concerns the gene TNFAIP3 and acute lymphoblastic leukemia.