The significant diagnostic markers of RA were gP350 IgG, gP350 IgA, gH/gL IgM, and gP42 IgA, while the markers of SLE included gP350 IgG, gP350 IgA, gH/gL IgA, and gP42 IgM. The gene discussed is CD40LG; the disease is rheumatoid arthritis.